Postdoctoral Scientist, San Antonio, Texas

The Role:

We are seeking a Post-Doctoral scientist to design, execute, and supervise research in biochemistry, microbiology, cellular biology, and immunology in the field of Tuberculosis (TB). Furthermore, the candidate will assist Dr. Jordi B. Torrelles to develop research goals for his lab; coordinate the development and implementation of new and/or revised research methodologies and techniques; plan, design and perform complex laboratory experiments and testing criteria, develop new laboratory techniques, and trouble-shoot protocols; collect, analyze and evaluate complex research data; set up, operate and maintain laboratory equipment; prepare manuscripts, articles, abstracts and research reports for publication in peer-reviewed journals; attend and present at national and international scientific conferences, workshops and seminars; assist with the development and preparation of grant proposals to obtain outside funding in support of research; conduct independent critical analysis of research literature related to research being investigated; train and/or manages work of undergraduate and graduate students, and other laboratory (or research) staff; monitor and enforce laboratory safety procedures to ensure compliance with OSHA and EHS regulations as well as human (IRB), animal (IACUC), radioactive, and biohazard (IBC) safety protocols; maintain laboratory notebooks; participates in seminars and activities; attend laboratory meetings; other duties as assigned.

DESIRED RESEARCH SKILLS

• Cell Biology: Required to have experience in isolation of primary (human) cells and cell line maintenance as well as performing in vitro infections; microscopic techniques (confocal and immunofluorescence microscopy).
• Microbiology: Required BSL-3 work experience with drug-susceptible and drug-resistant M. tuberculosis strains.
• Biochemistry: Required experience in basic and advanced biochemistry techniques such as microbial lipid extractions; 1D- and 2D-thin layer chromatography; liquid chromatography-mass spectrometry sample preparation and data analysis; lipoglycan extractions; SDS-PAGE gel preparation, running, and staining; mycolic acid extractions.
• Immunology: Required experience in ELISA; cytotoxicity assays; immunohistochemistry.

RESEARCH SKILLS (PREFERRED):

• Microbiology: Culture of virulent of Mycobacterium tuberculosis (M.tb); culture of non-pathogenic mycobacterial strains under BSL-2 conditions; phagocytosis assay; microbial cultures; colony forming unit enumeration.
• Software: Experience in proficient in Microsoft Word, Microsoft PowerPoint, Microsoft Excel, GraphPad Prism, ImageJ, Zeiss image viewer, MassHunter Qualitative Analysis 10, and Skyline Quantitative Analysis.

Our Ideal Candidate:

A highly motivated individual with a Ph.D. in Biomedical Sciences/Immunology, or a related discipline. Experience in the experimental design, implementation, performance, gathering of data and interpretation of results is required.

Who We Are:

Texas Biomedical Research Institute is one of the world's leading independent biomedical research institutions dedicated to advancing global human health through innovative biomedical research. Texas Biomed aims to unravel the mysteries of infectious diseases through innovative thinking, creative problem solving and cutting-edge technologies. The Southwest National Primate Research Center (SNPRC) provides broad services in primate research. We are one of seven National Primate Research Centers (NPRCs) with specialized technologies, capabilities and primate resources, many of which are unique to the SNPRC.

What We Can Offer You:

• Competitive pay

• 7% Employer-Funded retirement contribution starting day one

• Full insurance benefits

• Holidays, PTO and a paid week off in the last week of December

Texas Biomedical Research Institute provides equal employment opportunities for all qualified employees and applicants without regard to race, color, sex, sexual orientation, gender identity, religion, national origin, disability, veteran status, age, marital status, pregnancy, genetic information, or other legally protected status.

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